Adherence to the vegetable-fruit-soy diet pattern, which is a reference from the Mediterranean diet, protects Chinese women from postmenopausal breast cancer

The diet center hypothesis has gained much support from the apparent protective effect of the Mediterranean diet against breast cancer. However, evidence linking adherence to the Mediterranean diet to molecular subtypes of breast cancer remains inadequate, especially among non-Mediterranean populations. Method: The subject of the Wuxi exposure and breast cancer study in China is a population-based case-control study that includes 818 patients and 935 healthy controls. A modified version of the Validated Dietary Rating FFQ and Alternative Mediterranean Diet Score (aMED), the Alternative China Diet Score (aCHD) is to assess compliance with the migrated Chinese version of the Mediterranean diet called Vegetables-Fruits-Soybeans. A diet pattern developed in. Reflecting the region's cuisine, soy products, canola oil and coarse grains have replaced legumes, olive oil and whole grains. Vegetable-fruit-soybean stratified by menopausal state (pre-menopausal or post-menopausal) and receptor state (estrogen receptor (ER), progesterone receptor (PR) state, and human epithelial growth factor tumor gene) We investigated the association between dietary adherence and breast cancer risk Formula 2 (HER2) followed by five specific combinations (ER +, ER-, ER + / PR +, ER- / PR- and ER- / PR- / HER2-). The results show that the vegetable-fruit-soy diet pattern is inversely correlated with postmenopausal breast cancer risk (4th vs. 1st quartile, or 0.57, 95% CI = 0.41, 0.80; Ptrend <0.001). Correlation is slightly stronger in the ER subtype (OR = 0.63; 95% CI = 0.37, 0.94; P trend
= 0.003) and the ER / PR subtype (OR = 0.64, 95% CI = 0.41, 0.93, Ptrend = 0.012). No significant association was observed between the characteristics of the vegetable-fruit-soy diet and the ER + subtype, and between the PR + and ER + / PR + subtypes.  Conclusion: The beneficial effects of a Mediterranean diet also apply to Chinese women. The vegetable-fruit-soy diet pattern can reduce the risk of postmenopausal breast cancer, especially in the ER and ER / PR subtypes.

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